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Weight loss, in the context of medicine or health or physical fitness, is reduction of the total body weight, due to a mean loss of fluid, body fat or adipose tissue and lean mass, namely bone mineral deposits, muscle, tendon and other connective tissue. Weight loss refers to the loss of total body mass in an effort to improve fitness, health and appearance. Therapeutic weight loss, in individuals who are overweight or obese, can decrease the likelihood of developing diseases such as diabetes, heart disease, high blood pressure, stroke, osteoarthritis, and certain types of cancer. Weight loss occurs when an individual is in a state of negative energy balance. When the human body is spending more energy in work and heat than it is gaining from food or other nutritional supplements, it will use stored reserves of fat or muscle.
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